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Actinic keratosis

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Overview

Actinic keratosis (AK), also known as solar keratosis or senile keratosis, is a common skin condition characterized by the presence of rough, scaly patches or lesions on the skin. These lesions are considered precancerous, which means they have the potential to develop into skin cancer, typically squamous cell carcinoma, if left untreated. Actinic keratosis is primarily caused by long-term exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds.

While it is usually benign, untreated actinic keratosis lesions can progress to a more aggressive form of skin cancer. In this comprehensive article, we will explore actinic keratosis in detail, covering its causes, risk factors, types, symptoms, diagnosis, prevention strategies, treatment options, and guidance on when to seek medical attention.

Types of Actinic keratosis

Actinic keratosis can manifest in various forms, including:

1) Dry, Scaly Lesions: These are the most common and typically appear on sun-exposed areas like the face, ears, neck, scalp, chest, backs of hands, forearms, or lips.

2) Actinic Cheilitis: A variant affecting the lower lip, which may become rough, scaly, and discolored.

3) Cutaneous Horns: Rare, elevated growths that resemble small horns or thorns.

Causes of Actinic keratosis

The primary cause of actinic keratosis is prolonged exposure to UV radiation, whether from natural sunlight or artificial sources such as tanning beds. UV radiation damages the DNA in skin cells, leading to the development of these precancerous lesions.

Risk Factors of Actinic keratosis

Several factors may increase an individual's susceptibility to actinic keratosis:

  • Sun Exposure: Spending significant time outdoors without adequate sun protection increases the risk.
  • Fair Skin: People with fair skin, light hair, and blue or green eyes are more susceptible.
  • Age: Actinic keratosis is more common in older adults due to cumulative sun exposure.
  • Immune Suppression: Conditions or medications that weaken the immune system can raise the risk.

Symptoms of Actinic keratosis

The signs and symptoms of actinic keratosis can include:
1. Rough, Dry Patches: Skin areas that feel rough, dry, and scaly to the touch.
2. Itching or Burning: These areas may become itchy or painful, especially in response to UV exposure.
3. Color Changes: Actinic keratosis lesions can be pink, red, brown, or flesh-toned.
4. Small Bumps or Horns: Raised, hard bumps or growths, occasionally forming cutaneous horns.

Preventions of Actinic keratosis

Preventing actinic keratosis involves sun protection measures:

  • Sunscreen: Regularly apply broad-spectrum sunscreen with SPF 30 or higher.
  • Protective Clothing: Wear long sleeves, pants, wide-brimmed hats, and sunglasses.
  • Avoid Peak Sun Hours: Limit sun exposure between 10 a.m. and 4 p.m.
  • Seek Shade: Stay in the shade when outdoors.

Diagnosis of Actinic keratosis

Diagnosing actinic keratosis typically involves:

  • Physical Examination: A healthcare provider will assess the skin for lesions and evaluate their characteristics.
  • Biopsy: If a lesion appears suspicious, a biopsy may be performed to confirm the diagnosis.

Treatment for Actinic keratosis

Several treatment options are available for actinic keratosis, including:

  • Topical Medications: Creams or gels containing ingredients like fluorouracil, imiquimod, or diclofenac.
  • Cryotherapy: Freezing the lesions with liquid nitrogen.
  • Photodynamic Therapy (PDT): A light-activated chemical treatment.
  • Laser Therapy: Targeted laser treatment for more severe cases.
  • Surgical Removal: Excision or shave removal of lesions when necessary.

When to seek medical attention ?

Consult a healthcare provider if you notice any suspicious skin changes, such as rough, scaly patches or new growths. Early diagnosis and treatment can prevent the progression of actinic keratosis to skin cancer and protect your skin's health.

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