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Complex Regional Pain Syndrome (CRPS)

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Overview

Complex Regional Pain Syndrome (CRPS) is a debilitating condition characterized by severe, continuous pain that usually affects an arm or a leg. Let’s delve into the specifics:

What Is CRPS?

CRPS is a post-traumatic disorder that occurs after an injury or surgery. It disproportionately affects the affected limb, leading to intense pain, sensory changes, and other disturbances.

Incidence and Demographics

  • Incidence rates vary but can range from 5.5 to 26.2 cases per 100,000 person-years.
  • Women are more commonly affected than men, with the highest incidence in women aged 61–70 years.

Types of Complex Regional Pain Syndrome (CRPS)

CRPS has two distinct types:

CRPS Type I (Without Nerve Lesion)

  • No demonstrable nerve lesion.
  • Often triggered by minor trauma or surgery.
  • Presents with severe pain, swelling, and skin changes.

CRPS Type II (With Demonstrable Nerve Lesion)

  • Associated with a known nerve injury.
  • Similar clinical presentation to Type I.
  • Diagnosis based on clinical criteria.

Causes of Complex Regional Pain Syndrome (CRPS)

CRPS typically follows trauma or surgery. The pain is out of proportion to the initial injury and extends beyond the affected area. Common causes include fractures, sprains, and surgery.

Risk Factors of Complex Regional Pain Syndrome (CRPS)

everal risk factors increase the likelihood of developing CRPS:

Risk Factors:

  • Female gender
  • Fractures (especially wrist or ankle fractures)
  • Older age

Symptoms of Complex Regional Pain Syndrome (CRPS)

CRPS manifests with a variety of symptoms:
1. Sudden, Severe Pain: Persistent, burning, or throbbing pain.
2. Sensory Changes: Altered sensation (hypersensitivity or numbness).
3. Vasomotor Disturbances: Skin temperature changes, color variations.
4. Sudomotor/Oedema Changes: Excessive sweating or swelling.
5. Motor/Trophic Changes: Muscle weakness, nail/hair abnormalities.

Preventions of Complex Regional Pain Syndrome (CRPS)

While prevention is challenging, early recognition and prompt treatment can minimize disability. Educate patients about CRPS risk factors and encourage vigilance after injuries.

Diagnosis of Complex Regional Pain Syndrome (CRPS)

RPS diagnosis relies on clinical assessment:

Diagnostic Criteria:

  • New IASP criteria emphasize clinical signs and symptoms.
  • No specific diagnostic test exists.

Treatment for Complex Regional Pain Syndrome (CRPS)

A multidisciplinary approach is crucial:

Treatment Strategies:

  1. Pain Management:
    • Medications (analgesics, neuropathic agents)
    • Interventions (nerve blocks, sympathetic blocks)
  2. Physiotherapy:
    • Improve function and mobility.
  3. Psychological Support:
    • Address emotional aspects.
  4. Future Directions:
    • Mechanism-based treatments (e.g., immunomodulation).

When to seek medical attention ?

Seek medical attention promptly if you experience persistent limb pain, especially after trauma or surgery.

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