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Diabetes Mellitus

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Overview

Diabetes mellitus encompasses a group of chronic conditions affecting blood sugar (glucose) regulation. Glucose serves as the primary energy source for our cells, but in diabetes, its utilization is impaired. Let’s explore the different types, causes, symptoms, prevention strategies, complications, diagnosis, treatment, and when to seek medical attention.

Types of Diabetes Mellitus

1. Type 1 Diabetes

  • Description: An autoimmune disorder where the immune system attacks insulin-producing cells in the pancreas.
  • Onset: Typically diagnosed in childhood or adolescence.
  • Cause: Genetic predisposition.
  • Symptoms: Rapid onset, excessive thirst, frequent urination, weight loss, fatigue, and blurred vision.
  • Treatment: Requires lifelong insulin therapy
  • Relevance: Approximately 10% of people with diabetes have Type 1.

2.Type 2 Diabetes

    • Description: Characterized by insulin resistance and inadequate insulin production.
    • Onset: Commonly affects adults, but increasingly seen in children.
    • Cause: Lifestyle factors (obesity, sedentary habits, poor diet).
    • Symptoms: Gradual onset, similar to Type 1 but less severe.
    • Treatment: Lifestyle modifications, oral medications, and sometimes insulin.
    • Relevance: Most prevalent type of diabetes.

3. Prediabetes

    • Description: Elevated blood glucose levels not yet meeting the criteria for diabetes.
    • Cause: Lifestyle factors and genetic susceptibility.
    • Risk: Progression to Type 2 diabetes.
    • Prevention: Lifestyle changes (diet, exercise).
    • Relevance: Often undiagnosed; early intervention is crucial.

4. Gestational Diabetes

    • Description: Develops during pregnancy.
    • Cause: Hormonal changes affecting insulin sensitivity.
    • Risk: Increased risk of Type 2 diabetes later in life.
    • Management: Blood sugar monitoring, diet, and exercise.
    • Relevance: Usually resolves after childbirth.

Causes of Diabetes Mellitus

The exact causes vary by type:

  • Type 1: Autoimmune destruction of insulin-producing cells.
  • Type 2: Combination of genetic factors and lifestyle choices (obesity, poor diet).

Risk Factors of Diabetes Mellitus

Several factors increase the risk of developing diabetes:

  • Obesity: Excess body weight contributes to insulin resistance.
  • Physical Inactivity: Sedentary lifestyles impair insulin sensitivity.
  • Family History: Genetic predisposition.
  • Age: Type 2 diabetes is more common in individuals over 40.
  • Gestational Factors: Pregnancy-related diabetes increases the risk of Type 2 diabetes later in life.

Symptoms of Diabetes Mellitus

Common symptoms include:
1. Excessive Thirst (Polydipsia): Description: Feeling constantly thirsty, even after drinking water. Cause: Elevated blood sugar levels lead to dehydration. Significance: Often an early symptom of diabetes.
2. Frequent Urination (Polyuria): Description: Needing to urinate frequently, especially at night. Cause: High blood glucose levels overwhelm the kidneys. Significance: Excess sugar in urine leads to increased urine output.
3. Unexplained Weight Loss: Description: Losing weight unintentionally despite normal eating habits. Cause: Cells can’t access glucose for energy, so the body breaks down fat and muscle. Significance: Common in Type 1 diabetes and sometimes in Type 2.
4. Fatigue and Weakness: Description: Feeling tired and lacking energy. Cause: Glucose isn’t efficiently utilized by cells. Significance: Persistent fatigue warrants investigation.
5. Blurred Vision: Description: Vision becomes hazy or unclear. Cause: High blood sugar affects the lens of the eye. Significance: An indicator of poorly controlled diabetes.
6. Slow-Healing Sores and Infections: Description: Wounds take longer to heal, and infections are more frequent. Cause: Impaired blood flow and compromised immune function. Significance: Diabetes affects tissue repair.
7. Tingling or Numbness (Neuropathy): Description: Sensations of pins and needles or loss of feeling. Cause: Nerve damage due to prolonged high glucose levels. Significance: Can affect hands, feet, and other areas.
8. Increased Hunger (Polyphagia): Description: Feeling hungry frequently, even after eating. Cause: Cells are starved due to insulin resistance. Significance: Common in Type 2 diabetes.

Preventions of Diabetes Mellitus

  • Maintain a healthy weight.
  • Engage in regular physical activity.
  • Follow a balanced diet.
  • Monitor blood sugar levels if at risk.

Diagnosis of Diabetes Mellitus

  • Fasting blood sugar test
  • Oral glucose tolerance test
  • Hemoglobin A1c (HbA1c) test.

Treatment for Diabetes Mellitus

  • Lifestyle Modifications:
    • Diet: Balanced, low-sugar, portion-controlled.
    • Exercise: Regular physical activity.
    • Weight management.
  • Medications:
    • Oral antidiabetic drugs.
    • Insulin therapy (Type 1 and some Type 2 cases).
  • Regular Monitoring:
    • Blood sugar levels.
    • Blood pressure.
    • Lipid profile.

When to seek medical attention ?

If you experience symptoms or have risk factors, consult a healthcare provider promptly. Early diagnosis and management are essential for preventing complications.