Invasive Lobular Carcinoma

Overview

Invasive lobular carcinoma is a type of breast cancer that begins in the milk-producing glands of the breast, known as lobules. It is an aggressive and invasive cancer that spreads quickly to other parts of the body, making it a serious health concern for women. Invasive lobular carcinoma accounts for about 10% of all breast cancer cases and is more common in women over the age of 50.

Types of Invasive Lobular Carcinoma

1. Classic Invasive Lobular Carcinoma: This is the most common type of invasive lobular carcinoma, accounting for about 70% of all cases. It is characterized by the presence of single file cells that spread in a linear pattern.
2. Pleomorphic Invasive Lobular Carcinoma: This type of invasive lobular carcinoma is characterized by the presence of large, irregular cells that are often rounded or oval in shape.
3. Mixed Invasive Lobular Carcinoma: This type of invasive lobular carcinoma is characterized by the presence of both classic and pleomorphic cell types.

Causes of Invasive Lobular Carcinoma

• Genetic mutations: Genetic mutations in the BRCA1 and BRCA2 genes can increase the risk of developing invasive lobular carcinoma.
• Hormonal factors: Hormonal factors, such as estrogen and progesterone, can play a role in the development of invasive lobular carcinoma.
• Environmental factors: Exposure to environmental factors, such as radiation and certain chemicals, may also increase the risk of developing invasive lobular carcinoma.

Risk Factors of Invasive Lobular Carcinoma

• Age: Women over the age of 50 are at higher risk of developing invasive lobular carcinoma.
• Family history: Having a family history of breast cancer, particularly in relatives under the age of 50, can increase the risk.
• Genetic mutations: Women with genetic mutations in the BRCA1 and BRCA2 genes are at higher risk of developing invasive lobular carcinoma.
• Previous breast cancer: Women who have had a previous diagnosis of breast cancer are at higher risk of developing invasive lobular carcinoma.

Symptoms of Invasive Lobular Carcinoma

Preventions of Invasive Lobular Carcinoma

• Mammography screenings: Regular mammography screenings can help detect invasive lobular carcinoma early on.
• Breast self-examination: Women should perform regular breast self-examinations to detect any changes in their breasts.
• Healthy lifestyle choices: Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can help reduce the risk of developing invasive lobular carcinoma.

Diagnosis of Invasive Lobular Carcinoma

• Mammography: Mammography is often used to diagnose invasive lobular carcinoma.
• Biopsy: A biopsy is typically performed to confirm the diagnosis.
• Imaging tests: Imaging tests, such as CT scans and MRI scans, may be used to evaluate the extent of the disease.

Treatment for Invasive Lobular Carcinoma

1. Surgery: Surgery is often used to remove the tumor and affected tissue.
2. Chemotherapy: Chemotherapy may be used to treat invasive lobular carcinoma that has spread to other parts of the body.
3. Hormone therapy: Hormone therapy may be used to treat invasive lobular carcinoma that is sensitive to hormones.

When to seek medical attention ?

1. Breast lump or thickening: If you notice a lump or thickening in your breast, seek medical attention immediately.
2. Nipple retraction or discharge: If you notice nipple retraction or discharge, seek medical attention immediately.
3. Unusual changes in your breasts: If you notice any unusual changes in your breasts, seek medical attention immediately.