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Lobular Carcinoma in Situ (LCIS)

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Overview

Lobular carcinoma in situ (LCIS) is an uncommon condition that occurs when abnormal cells grow in the milk glands (lobules) of the breast. The condition is not cancerous, but it is considered a high-risk lesion for breast cancer. LCIS is often diagnosed incidentally during a breast biopsy done for another reason.

Types of Lobular Carcinoma in Situ (LCIS)

There are two types of LCIS:

  1. Classical LCIS: This type of LCIS is characterized by abnormal cell growth in the milk glands.
  2. Atypical LCIS: This type of LCIS is characterized by abnormal cell growth in the milk glands and ducts.

Causes of Lobular Carcinoma in Situ (LCIS)

The exact cause of LCIS is unknown, but it is believed to be related to genetic mutations and hormonal influences. Women with a family history of breast cancer are more likely to develop LCIS.

Risk Factors of Lobular Carcinoma in Situ (LCIS)

The following factors may increase the risk of developing LCIS:

  1. Family history: Women with a family history of breast cancer are more likely to develop LCIS.
  2. Genetic mutations: Women with genetic mutations such as BRCA1 or BRCA2 are more likely to develop LCIS.
  3. Hormonal influences: Hormonal fluctuations during pregnancy or menstruation may increase the risk of developing LCIS.
  4. Age: Women over the age of 50 are more likely to develop LCIS.

Symptoms of Lobular Carcinoma in Situ (LCIS)

LCIS usually does not show any symptoms until it has progressed to an advanced stage. However, women with LCIS may experience symptoms such as:
1. Breast Tenderness
2. Breast lump.
3. Breast pain.
4. Nipple discharge.
5. Changes in the size or shape of the breast.

Preventions of Lobular Carcinoma in Situ (LCIS)

There is no known way to prevent LCIS from developing. However, women with a family history of breast cancer or genetic mutations may benefit from regular breast cancer screenings and risk-reducing medications.

Diagnosis of Lobular Carcinoma in Situ (LCIS)

Diagnosis of LCIS typically involves a combination of the following methods:

  1. Mammography: A mammogram may be used to detect abnormalities in the breast tissue.
  2. Ultrasound: An ultrasound may be used to evaluate the size and shape of the breast lump.
  3. Biopsy: A biopsy may be performed to confirm the diagnosis of LCIS.

Treatment for Lobular Carcinoma in Situ (LCIS)

Treatment for LCIS typically involves a combination of the following methods:

  1. Surgery: Surgical removal of the affected breast tissue may be necessary.
  2. Radiation therapy: Radiation therapy may be used to reduce the risk of developing breast cancer.
  3. Chemotherapy: Chemotherapy may be used to treat any underlying cancer.
  4. Hormone therapy: Hormone therapy may be used to reduce the risk of developing breast cancer.

When to seek medical attention ?

Women with any symptoms or concerns about their breasts should consult with their doctor.

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