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Peyronie’s Disease

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Overview

Peyronie’s disease, also known as induratio penis plastica, is a condition characterized by the development of fibrous scar tissue (plaque) within the deeper tissues of the penis. This scar tissue causes the penis to curve or bend during erections, leading to pain and potential complications. Although it’s not caused by cancer, Peyronie’s disease can significantly impact a man’s quality of life.

Types of Peyronie’s Disease

There are several types of Peyronie’s disease based on the location of the scar tissue:

  1. Dorsal Plaque: Scar tissue on the top of the shaft causes an upward bend during erection.
  2. Lateral Plaque: Plaque on the side results in a lateral (sideways) curvature.
  3. Ventral Plaque: Scar tissue on the underside leads to a downward bend .

Causes of Peyronie’s Disease

The exact cause of Peyronie’s disease remains unclear, but several factors may contribute:

  • Repetitive Trauma: Repeated injury to the penis during sexual activity or physical strain can trigger scar tissue formation.
  • Genetics: Family history suggests a genetic predisposition.
  • Age: Although it can occur at any age, it’s more common in men aged 50s and 60s .

Risk Factors of Peyronie’s Disease

Risk factors for Peyronie’s disease include:

  • Family History: A family history of the condition increases the risk.
  • Age: As mentioned earlier, older men are more susceptible.
  • Trauma: Previous penile injuries or surgeries.
  • Connective Tissue Disorders: Conditions like Dupuytren’s contracture may be associated.

Symptoms of Peyronie’s Disease

Common symptoms include:
1. Scar Tissue: Palpable plaque under the skin.
2. Penile Curvature: Upward, downward, or lateral bending.
3. Erectile Dysfunction in Men: Difficulty achieving or maintaining an erection.
4. Penile Shortening: Reduced length during erections.
5. Pain: Pain during erections or even at rest .

Preventions of Peyronie’s Disease

Unfortunately, there are no specific preventive measures for Peyronie’s disease. However, avoiding traumatic injuries to the penis may reduce the risk.

Diagnosis of Peyronie’s Disease

Diagnosis involves physical examination and ultrasound imaging to detect scar tissue. Early treatment is crucial for better outcomes.

Treatment for Peyronie’s Disease

Options include:

  • Medication: Pentoxifylline, collagenase, verapamil, and interferon.
  • Surgery: Plication, incision and grafting, iontophoresis, or penile implant surgery.

When to seek medical attention ?

Seek medical attention if you experience symptoms of Peyronie’s disease. Early intervention improves outcomes.

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