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Undifferentiated pleomorphic sarcoma (UPS)

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Overview

Undifferentiated pleomorphic sarcoma (UPS) is a rare type of cancer that begins in the soft tissues of the body. Soft tissues connect, support and surround other body structures. UPS is a type of soft tissue sarcoma that typically occurs in the arms or legs, but can also occur in the retroperitoneum.

Types of Undifferentiated pleomorphic sarcoma (UPS)

UPS is a type of soft tissue sarcoma that is characterized by its undifferentiated and pleomorphic cells. The cells do not resemble the body tissues in which they develop and grow in multiple shapes and sizes.

Causes of Undifferentiated pleomorphic sarcoma (UPS)

The exact cause of UPS is not known, but it is believed to be related to genetic mutations. Genetic mutations can occur spontaneously or be inherited from one's parents.

Risk Factors of Undifferentiated pleomorphic sarcoma (UPS)

The following factors may increase the risk of developing UPS:

  • Family history: A family history of UPS or other types of soft tissue sarcoma may increase the risk.
  • Genetic mutations: Certain genetic mutations such as TP53 mutations may increase the risk.
  • Radiation exposure: Exposure to radiation may increase the risk of developing UPS.

Symptoms of Undifferentiated pleomorphic sarcoma (UPS)

The symptoms of UPS can vary depending on the location and size of the tumor. Common symptoms include:
1. A lump or swelling in the arm or leg.
2. Pain or discomfort in the affected area.
3. Limited mobility or stiffness in the affected area.
4. Swelling or redness in the affected area.

Preventions of Undifferentiated pleomorphic sarcoma (UPS)

There is no known way to prevent UPS, but early detection and treatment can improve outcomes.

Complications: If left untreated, UPS can lead to complications such as:

  • Metastasis to other parts of the body.
  • Recurrence of the tumor.
  • Spread of the tumor to other parts of the body.

Diagnosis of Undifferentiated pleomorphic sarcoma (UPS)

Diagnosing UPS typically involves a combination of:

  • Physical examination and medical history.
  • Imaging studies such as MRI or CT scans to confirm the diagnosis.
  • Biopsy to confirm the presence of cancer cells.

Treatment for Undifferentiated pleomorphic sarcoma (UPS)

Treatment for UPS typically involves a combination of:

  • Surgery to remove the tumor.
  • Radiation therapy to kill cancer cells.
  • Chemotherapy to kill cancer cells.

When to seek medical attention ?

If you suspect that you have UPS, it is important to seek medical attention promptly. Delaying treatment can lead to complications and worsen symptoms.

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